Την Τρίτη, 13 Ιουνίου, ώρα 16:00, θα πραγματοποιηθεί τηλεδιάλεξη με θέμα:
“Microfluidics for Chemistry, Biology and Diagnostics”
Oμιλητές: Andrew DeMello, Professor of Biochemical Engineering in the Department of Chemistry and Applied Biosciences at ETH Zurich and Head of the Institute for Chemical and Bioengineering, Zurich, Switzerland
Stavros Stavrakis, Senior Scientist, Institute for Chemical and Bioengineering, ETH Zürich, Switzerland
Η τηλεδιάλεξη πραγματοποιείται στο πλαίσιο του μεταπτυχιακού προγράμματος ‘Αναλυτική Χημεία & Νανοτεχνολογία’, του Τμήματος Χημείας, διακρίνεται από διεπιστημονικότητα και απευθύνεται σε ευρύ ακροατήριο.
Σύνδεσμος:
Join Zoom Meeting
https://upatras-gr.zoom.us/j/95210238427?pwd=VSs0TzMwemZSeTFLWVBoR0p4Z0NVQT09
Meeting ID: 952 1023 8427
Passcode: 435385
Περίληψη
The past three decades have seen considerable progress in the development of microfluidic systems for use in the chemical and biological sciences. Interest in microfluidic technology has been driven by concomitant advances in the areas of genomics, proteomics, drug discovery, high-throughput screening and diagnostics, with a need to perform rapid measurements on small sample volumes. At a basic level, microfluidic activities have been stimulated by the fact that physical processes can be more easily controlled when instrumental dimensions are reduced to the micron scale.
First, Andrew will discuss the features and application of droplet-based microfluidic systems. Such systems generate, manipulate and control sub-microliter droplets enclosed within an immiscible carrier fluid. Owing to a number of remarkable features, such as the ability to precisely control the chemical and biological payload of each droplet and to produce thousands of droplets per second, this technology is transforming how chemists and biologists perform high-throughput or massively parallel experiments. He will provide examples of how droplet-based microfluidic systems can be used to perform a range of experiments including nanomaterial synthesis, cell-based assays and the directed evolution of enzymes.
The considerable advantages that are afforded through the use of microfluidic systems are made possible by system downscaling and associated improvements in mass and thermal transfer. Nonetheless, handling and processing fluids with instantaneous volumes on the fL-nL scale represents a critical challenge for molecular detection, and still defines one of the key limitations in the use of a microfluidic system in a given application. Accordingly, Stavros will describe how the application of novel optical techniques ensures that rates of information extraction can match rates of information generation. He will present novel microfluidic platforms for imaging flow cytometry that leverage elasto-inertial microfluidics and stroboscopic illumination to allow for high-resolution imaging of cells at throughputs approaching half a million cells per second.
Short CVs
Andrew is currently Professor of Biochemical Engineering in the Department of Chemistry and Applied Biosciences at ETH Zurich. His research interests cover a broad range of activities in the general area of microfluidics and nanoscale science. Specializations include the development of microfluidic devices for high-throughput biological and chemical analysis, ultra-sensitive optical detection techniques and point-of-care diagnostics.
Stavros received his B.Sc. in Chemistry from the University of Crete in 1999. In 2005 he was awarded a Ph.D. in Biophysical Chemistry from the University of Crete for his work on time-resolved vibrational spectroscopy of cytochrome oxidases. Prior to moving to Zurich in 2011 he held a Marie Curie Fellowship at Stanford University in the group of Prof. Stephen Quake. During this period, he developed new optical tools for single molecule DNA sequencing platforms. Stavros moved to ETH Zurich in 2011 and is currently a Senior Scientist in the Institute for Chemical and Bioengineering. His current research interests are focused on applications of single molecule fluorescence detection, and optofluidics in biology. He leads a team of postdocs and graduate students developing new microfluidic platforms for single molecule enzymology, high-throughput imaging flow cytometry, ultrafast enzyme kinetics and single-cell screening.
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Δέσποινα Καλογιάννη
Επίκουρη Καθηγήτρια Αναλυτικής Χημείας & Νανοτεχνολογίας
Τμήμα Χημείας